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Tocris Bioscience™ ISO 1
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Product Code. 30002044
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Product Code. 30002044 Supplier Tocris Bioscience™ Supplier No. 4288/50

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Description

Macrophage migration inhibitory factor (MIF) inhibitor

ISO 1 is a macrophage migration inhibitory factor (MIF) inhibitor (IC50 = 7 μM); inhibits MIF tautomerase activity in vitro and in vivo. Protective against mouse models of streptozotocin -induced diabetes mellitus; blocks anti-inflammatory response following LPS exposure and increases survival. Inhibits airway remodeling in a mouse model of chronic asthma. Cell permeable; orally bioavailable.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 478336-92-4
Molecular Formula C12H13NO4

Specifications

Quantity 50 mg
Formula Weight 235.24
Physical Form Solid
Color White
Purity >98%
Molecular Weight (g/mol) 235.239
Chemical Name or Material ISO 1
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