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Invitrogen™ IL-10 Recombinant Human Monoclonal Antibody (1C7)
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Human Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA560761

Product Code. 30534040

  • 459.00€ / 100µL

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Description

Description

IL-10 Recombinant Monoclonal Antibody for IHC (P), ELISA

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
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Specifications

Specifications

IL-10
Recombinant Monoclonal
4.26 mg/mL
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
P22301
IL10
Recombinant Human IL10 protein.
100 μL
Primary
Human
Antibody
IgG1
ELISA, Immunohistochemistry (Paraffin)
1C7
Unconjugated
IL10
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Human
Affinity chromatography
RUO
3586
-20°C or -80°C if preferred
Liquid
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