missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ ICAM3 Monoclonal Antibody (76205)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561915
This item is not returnable.
View return policy
Description
Reconstitute at 0.5 mg/mL in sterile PBS.
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
Specifications
| ICAM3 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P32942 | |
| ICAM3 | |
| Mouse myeloma cell line NS0-derived recombinant human ICAM-3/CD50, Gln30-His485. | |
| 500 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Inhibition Assays, Western Blot | |
| 76205 | |
| Unconjugated | |
| ICAM3 | |
| CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 3385 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction