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ACROBiosystems Human Plexin B2 Protein, His Tag

Brand:  ACROBiosystems PL2-H52H3-100ug

Additional Details : Weight : 0.00010kg

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Product Code. 17206420

  • 457.25€ / 100µg
Estimated Shipment: 26-04-2024
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Description

Description

Plexin B2 serves as the receptor of Sema4C and Sema4G. By signaling the effect of Sema4C and Sema4G, the plexin B2 receptor plays important roles in neural tube closure and cerebellar granule cell development. Mice lacking Plexin B2 demonstrated defects in closure of the neural tube and disorganization of the embryonic brain. In developing kidney, Sema4C-Plexin B2 signaling modulates ureteric branching. Plexin B2 is expressed both in the pretubular aggregates and the ureteric epithelium in the developing kidney. Deletion of Plexin B2 results in renal hypoplasia and occasional double ureters. The Sema domain is located at the N-terminus and contains four disulfide bonds formed by eight conserved cysteine residues. It serves as a ligand-recognition and -binding module.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 126.9 kDa.
Specifications

Specifications

126.9 kDa
Human Plexin B2, His Tag (PL2-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Arg 1160 (Accession # O15031-1).
-20°C
Plexin B2
Human
HEK293
Other Recombinant Proteins
100 μg
Leu 20 - Arg 1160
Plexin B2,PLXNB2,KIAA0315,MM1,Plexin-B2
Unconjugated
His Tag
Powder
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