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Abnova™ Human PAK7 kinase domain (Q9P286, 425 a.a. - 719 a.a.) Partial Recombinant Protein

Product Code. 16141850
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Quantity:
10 μg
Unit Size:
10µg
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16141850 10 μg 10µg
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Product Code. 16141850 Supplier Abnova™ Supplier No. P5385.10ug

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Description

Used for Func, SDS-PAGE

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Specifications

Accession Number Q9P286
Concentration 1 mg/ml
For Use With (Application) Functional Study, SDS-PAGE
Formulation Liquid
Gene ID (Entrez) 57144
Molecular Weight (g/mol) 33.9kDa
Name PAK7 (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Quality Control Testing Loading 12 ug protein in SDS-PAGE
Quantity 10 μg
Immunogen GPHMSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAIRRIRDSLPPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH The first 4 residues GPHM are from Turbo3C Protease cleavage site. The underlined S is phosphorylated S602.
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias KIAA1264/MGC26232/PAK5
Common Name PAK7
Gene Symbol PAK7
Biological Activity Specific activity: 4,199pmoles/min/μg
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Liquid
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