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Abnova™ Human PAK2 kinase domain (Q13177, 227 a.a. - 524 a.a.) Partial Recombinant Protein

Product Code. 16121850
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Quantity:
10 μg
Unit Size:
10µg
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16121850 10 μg 10µg
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Product Code. 16121850 Supplier Abnova™ Supplier No. P5383.10ug

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Description

Used for Func, SDS-PAGE

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq]

Specifications

Accession Number Q13177
Concentration 1 mg/ml
For Use With (Application) Functional Study, SDS-PAGE
Formulation Liquid
Gene ID (Entrez) 5062
Molecular Weight (g/mol) 33.5kDa
Name PAK2 (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Quality Control Testing Loading 6 ug protein in SDS-PAGE
Quantity 10 μg
Immunogen GPHMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR The first 4 residues GPHM are from Turbo3C Protease cleavage site. The underlined T is phosphorylated T402.
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias PAK65/PAKgamma
Common Name PAK2
Gene Symbol PAK2
Biological Activity Specific activity: 85,806pmoles/min/μg
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Liquid
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