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Abnova™ Human PAK1 kinase domain (Q13153, 248 a.a. - 545 a.a.) Partial Recombinant Protein

Codice prodotto. 16111850
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Quantity:
10 μg
Dimensione della confezione:
10µg
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Codice prodotto. Quantity unitSize
16111850 10 μg 10µg
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Codice prodotto. 16111850 Fornitore Abnova™ N. del fornitore P5382.10ug

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Descrizione

Used for Func, SDS-PAGE

PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifica

Accession Number Q13153
Concentration 1 mg/ml
For Use With (Application) Functional Study, SDS-PAGE
Formulation Liquid
Gene ID (Entrez) 5058
Molecular Weight (g/mol) 33.7kDa
Name PAK1 (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Quality Control Testing Loading 8 ug protein in SDS-PAGE
Quantity 10 μg
Immunogen GPHMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH The first 4 residues GPHM are from Turbo3C Protease cleavage site. The underlined T is phosphorylated T423.
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias MGC130000/MGC130001/PAKalpha
Common Name PAK1
Gene Symbol PAK1
Biological Activity Specific activity: 32,638pmoles/min/μg
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Liquid
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