missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. 16008246

Abnova™ Human DMPK (AAA75236.1, 1 a.a. - 544 a.a.) Partial Recombinant Protein with GST-tag expressed in baculovirus infected Sf21 cells

Product Code. 16008246
Change view
Click to view available options
:
5μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code.
16008246 5μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 16008246 Supplier Abnova™ Supplier No. P5536.5ug

Please to purchase this item. Need a web account? Register with us today!

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on +351 21 425 33 50 for assistance
 View alternative products

This item is not returnable. View return policy

Description

Used for Func, SDS-PAGE

The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]

Specifications

Accession Number AAA75236.1
For Use With (Application) Functional Study, SDS-PAGE
Formulation Liquid
Gene ID (Entrez) 1760
Molecular Weight (g/mol) 88kDa
Name DMPK (Human) Recombinant Protein
Preparation Method Baculovirus infected insect cell (Sf21) expression system
Purification Method Glutathione sepharose chromatography
Quality Control Testing Loading 1 ug protein in SDS-PAGE
Quantity 5 ug
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias DM/DM1/DM1PK/DMK/MDPK/MT-PK
Common Name DMPK
Gene Symbol DMPK
Biological Activity The activity was determined by ELISA. The enzyme was incubated with GST-fused substrate protein, and after stopping kinase reaction by EDTA, the reaction solution was transferred into glutathione- coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG. Substrate: MYPT1. ATP: 100 uM.
Species Baculovirus
Recombinant Recombinant
Protein Tag GST
Expression System Baculovirus infected insect cell (Sf21) expression system
Form Liquid
Purity or Quality Grade 82% by SDS-PAGE/CBB staining
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.