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GMPS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16805984 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16805984 20 μL 20µL
16895974 150 μL 150µL
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Product Code. 16805984 Supplier Proteintech Supplier No. 163761AP20UL

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Description

Rabbit Polyclonal Antibody

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Specifications

Antigen GMPS
Applications Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Classification Polyclonal
Concentration 0.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GMPS
Gene Accession No. P49915, Q3THK7, Q4V7C6
Gene Alias Glutamine amidotransferase, GMP synthetase, GMPS
Gene Symbols Gmps
Host Species Rabbit
Immunogen GMPS Fusion Protein Ag9350
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 229363, 295088, 8833
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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