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Invitrogen™ GDF15 Monoclonal Antibody (1005038)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA562039
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
Specifications
| GDF15 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q99988 | |
| Gdf15 | |
| E. coli-derived recombinant human GDF-15, Ala197-Ile308. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Immunocytochemistry | |
| 1005038 | |
| Unconjugated | |
| Gdf15 | |
| Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 9518 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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