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Novus Biologicals™ Flagellin Native Protein

Product Code. 18374624 Shop All Bio Techne Products
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Quantity:
100 μg
Unit Size:
100µg
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18374624 100 μg 100µg
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Product Code. 18374624 Supplier Novus Biologicals™ Supplier No. NBP318154

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Description

Native Protein

Binds to human & mouse TLR5. Activation of TLR5 in human epithelial cell assays based on NF-kB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 & matrilysin (MMP-7). Maturation of dendritic cells in in vitro & in vivoassays. Adjuvant activity on foreign antigens delivered by subcutaneous & intranasal routes in mice. TLR5 can be stimulated in vitro by Flagellin 5-50ng/mL & in vivo at a starting concentration of 0.1-1 ug/mouse.)
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P06179
Concentration LYOPH
For Use With (Application) Bioactivity, ELISA
Formulation Lyophilized from PBS
Quantity 100 μg
Storage Requirements Store at 4C short term. Aliquot and Store at -20°C long term. Avoid freeze-thaw cycles.
Endotoxin Concentration <0.1 EU/μg purified protein (LAL test; Lonza).
Reconstitution Reconstitute with 100 ul sterile water (1mg/ml after reconstitution)
Research Category Immunology, Innate Immunity
Purity or Quality Grade >90% SDS-PAGE
Protein Flagellin
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