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  6. Factor X Mouse anti-Human, Clone: 3D3F11, Proteintech

Factor X Mouse anti-Human, Clone: 3D3F11, Proteintech

Product Code. 16888915 Shop All Proteintech Products
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150 μL
20 μL
Unit Size:
150µL
20µL
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16888915 20 μL 20µL
16878915 150 μL 150µL
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Product Code. 16888915 Supplier Proteintech Supplier No. 667531IG20UL

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Description

Mouse Monoclonal Antibody

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Specifications

Antigen Factor X
Applications Western Blot
Classification Monoclonal
Clone 3D3F11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene F10
Gene Accession No. P00742
Gene Alias coagulation factor X, F10, Factor X, FX, FXA, Stuart factor, Stuart Prower factor
Gene Symbols F10
Host Species Mouse
Immunogen Factor X Fusion Protein Ag11664
Purification Method Protein G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2159
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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