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Description
Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Epithelial fatty acid-binding protein (E-FABP) binds stearic acid and may play a role in keratinocyte differentiation. E-FABP is upregulated in rat dorsal root ganglia after sciatic nerve crush and in differentiating neurons during development.
Specifications
Specifications
| Antigen | FABP5 |
| Applications | Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.43 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | FABP5 |
| Gene Accession No. | P55053, Q01469, Q05816 |
| Gene Alias | E FABP, EFABP, FABP5, Fatty acid binding protein 5, PA FABP, PAFABP |
| Gene Symbols | FABP5 |
| Show More |
Product Title
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