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ESRP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 23117-1-AP-20UL

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Product Code. 16822205

  • 145.00€ / 20µL

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Description

Description

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5′ UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
Specifications

Specifications

ESRP2
Polyclonal
Unconjugated
ESRP2
ESRP2, RBM35B, RNA binding motif protein 35B, RNA binding protein 35B
Rabbit
Antigen Affinity Chromatography
RUO
77411, 80004
-20°C
Liquid
Western Blot
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8K0G8, Q9H6T0
Esrp2
ESRP2 Fusion Protein Ag19436
20 μL
Primary
Mouse, Human
Antibody
IgG
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