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EMR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen EMR1
Concentration 0.47 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16805345
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Proteintech
27044-1-AP-20UL
20 μL
145.00€
20µL
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16895335
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Proteintech
27044-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.
Specifications

Specifications

EMR1
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human, Mouse
Q14246, Q61549
13733, 2015
EMR1 Fusion Protein Ag25883
Primary
-20°C
ADGRE1
0.47 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ADGRE1, Adhesion G protein-coupled receptor E1, EGF like module receptor 1, EMR1, EMR1 hormone receptor, F4/80, TM7LN3
ADGRE1
IgG
Antigen Affinity Chromatography
Antibody
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