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ELAVL2 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech
Shop All Proteintech ProductsDescription
The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintece. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM), and they specifically bind to AU-rich elements (ARE) in the 3′-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation.
Specifications
Specifications
| Antigen | ELAVL2 |
| Applications | Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 0.37 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | ELAVL2 |
| Gene Accession No. | Q12926, Q60899, Q8CH84 |
| Gene Alias | ELAV like neuronal protein 1, ELAV like protein 2, ELAV2, ELAVL2, HEL N1, HELN1, Hu antigen B, HUB |
| Gene Symbols | Elavl2 |
| Show More |
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