Invitrogen™ DPCR1 Monoclonal Antibody (986124)

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

The DPCR1 gene, known as diffuse panbronchiolitis critical region 1, encodes a protein involved in immune responses and epithelial cell function, particularly in the respiratory system. Although the specific functions of DPCR1 are not extensively characterized, the gene is located within a region linked to diffuse panbronchiolitis, a chronic inflammatory lung disease. DPCR1 is thought to contribute to immune regulation, potentially influencing innate immune responses and epithelial cell interactions critical for maintaining respiratory health. Its expression in airway epithelial cells suggests a role in modulating mucus production, barrier integrity, and protection against pathogens. Aberrant expression of DPCR1 may impact respiratory function, contributing to conditions such as asthma or chronic obstructive pulmonary disease (COPD) by affecting immune responses and inflammation. Understanding DPCR1's functions and regulatory mechanisms in the respiratory system is essential for exploring its potential as a therapeutic target for respiratory diseases characterized by chronic inflammation and immune dysregulation.