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DOK7 Monoclonal Antibody (OTI1D11), TrueMAB™, OriGene
Description
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | DOK7 |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI1D11 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | DOK7 |
| Gene Accession No. | Q18PE1 |
| Gene Alias | C4orf25, CMS10, CMS1B |
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Product Title
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