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Eurofins DiscoverX DMPK Protein, Active

Product Code. 17340494
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250 μg
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250µg
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17340494 10 μg 10µg
17350494 250 μg 250µg
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Product Code. 17340494 Supplier Eurofins DiscoverX Supplier No. 14649

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Description

Active, 6His-tagged, recombinant, human DMPK, amino acids 1-549, for use in Kinase Assays.

Myotonic dystrophy (DM1) is the most common form of muscular dystrophy in adults, caused by amplification of an unstable (CTG)n repeat in the 3' untranslated region (3'-UTR) of the DM1 protein kinase (DMPK) gene. Myotonic dystrophy protein kinase (DMPK) is a serine threonine kinase encoded by the DM-1 locus.

GenBank NM_004409

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 65 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Truncated
Purity or Quality Grade ≥66%
Protein DMPK, active
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