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Invitrogen™ DHH Monoclonal Antibody (148644)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561074
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signaling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Specifications
| DHH | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q61488 | |
| Dhh | |
| E. coli-derived recombinant mouse Desert Hedgehog/Dhh C-Terminus, Cys199-Gly396. | |
| 500 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 148644 | |
| Unconjugated | |
| Dhh | |
| C78960; desert hedgehog; desert hedgehog protein; Desert hedgehog protein C-product; Desert hedgehog protein N-product; Dhh; GDXYM; HHG-3; SRXY7 | |
| Rat | |
| Protein A/G | |
| RUO | |
| 13363 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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