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Invitrogen™ DGKQ Monoclonal Antibody (652308)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561692
This item is not returnable.
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Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4, 5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.
Specifications
| DGKQ | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P52824, Q6P5E8 | |
| DGKQ | |
| E. coli-derived recombinant human DGK-theta , Asp696-Lys839. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Western Blot | |
| 652308 | |
| Unconjugated | |
| DGKQ | |
| 110kDa; DAG kinase theta; DAGK; Dagk4; DAGK7; Dgk theta; Dgkd; DGKQ; DGK-theta; Diacylglycerol kinase theta; diacylglycerol kinase, delta (110 kDa); diacylglycerol kinase, theta; diacylglycerol kinase, theta 110kDa; diglyceride kinase theta; testis tissue sperm-binding protein Li 38a | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 100361138, 110524, 1609 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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