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ACROBiosystems Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc Tag
Brand: ACROBiosystems BCA-C5253-100UG
Additional Details : Weight : 0.00001kg
Description
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| XP_001106892.1 | |
| 100 μg | |
| Met 1 - Ala 53 | |
| TNFRSF17,CD269,BCM,BCMA | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 32.1 kDa | |
| Cynomolgus / Rhesus macaque BCMA, Fc Tag (BCA-C5253) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 53 (Accession # G7Q0I4-1). In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus. | |
| -20°C | |
| BCMA | |
| Cynomolgus Monkey, Rhesus Macaque | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |