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Tocris Bioscience™ CP 673451, Tocris Bioscience™
GREENER_CHOICE

Potent and selective PDGFR inhibitor

Brand:  Tocris Bioscience™ 5993/10

Encompass

Product Code. 15747186

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Description

Description

CP 673451 is a potent and selective PDGFR inhibitor (IC50 values are 1 and 10 nM for PDGFR-β and -α respectively). Selective for PDGFR kinase over a range of related kinases. Inhibits PDGFR-β phosphorylation in glioblastoma xenografts and PDGF-induced angiogenesis in mice.
Specifications

Specifications

1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine
10 mg
Solid
Bioactive Small Molecule
343787-29-1
Soluble to 100mM in water and to 100mM in DMSO
White
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