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  6. CFLAR/FLIP Rabbit anti-Human, Polyclonal, Proteintech

CFLAR/FLIP Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16886753 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16886753 20 μL 20µL
16876753 150 μL 150µL
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Product Code. 16886753 Supplier Proteintech Supplier No. 103941AP20UL

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Description

Rabbit Polyclonal Antibody

FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.

Specifications

Antigen CFLAR/FLIP
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunofluorescence
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CFLAR
Gene Accession No. O15519
Gene Alias c FLIP, c FLIPL, c FLIPR, c FLIPS, CASH, CASP8AP1, Caspase eight related protein, Caspase homolog, Casper, CFLAR, CLARP, FLAME, FLAME 1, FLAME1, FLIP, I FLICE, Inhibitor of FLICE, MRIT, Usurpin
Gene Symbols CFLAR
Host Species Rabbit
Immunogen CFLAR/FLIP Fusion Protein Ag0593
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8837
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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