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Abnova™ CDK4 Recombinant Protein

Human CDK4 full-length ORF recombinant protein with GST-tag at N-terminal

335.00€ - 508.00€

Specifications

Accession Number AAH03644
For Use With (Application) Antibody Production, Protein Array, ELISA, Western Blot
Formulation 50mM Tris HCl, 10mM reduced Glutathione, pH 8 in the Elution Buffer
Gene ID (Entrez) 1019
Molecular Weight (g/mol) 35.97
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16193011
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Abnova™
H00001019-P01.10UG
10 ug
335.00€
10µg
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Estimated Shipment: 07-05-2024
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16103021
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Abnova™
H00001019-P01.25UG
25 ug
508.00€
25µg
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Estimated Shipment: 07-05-2024
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Description

Description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

  • Theoretical MW (kDa): 35.97
  • Preparation method: In vitro wheat germ expression system
  • Purification: Glutathione Sepharose 4 fast flow
  • Storage buffer: 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer

Sequence: KPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE

Best use within three months from the date of receipt of this protein.

ELISA, Western Blotting (Recombinant Protein), Antibody Production, Protein Array

Specifications

Specifications

AAH03644
50mM Tris HCl, 10mM reduced Glutathione, pH 8 in the Elution Buffer
35.97
8
Glutathione Sepharose 4 Fast Flow
Wheat Germ (in vitro)
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
CDK4
Human
Recombinant
Solution
Antibody Production, Protein Array, ELISA, Western Blot
1019
CDK4 (Human) Recombinant Protein (P01)
In vitro wheat germ expression system
12.5% SDS-PAGE Stained with Coomassie Blue.
KPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE
CMM3/MGC14458/PSK-J3
CDK4
Wheat Germ (in vitro)
GST
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SDS
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