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CD4 Mouse, anti-Human, R718, Clone: SK3, BD Horizon™

Mouse Monoclonal Antibody

Brand:  BD Biosciences 566931

Additional Details : Weight : 0.00020kg

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Product Code. 17207724

  • 183.00€ / 25 tests
Estimated Shipment: 06-05-2024
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Description

Description

The SK3 monoclonal antibody specifically binds to CD4. The CD4 antigen is a 55 kDa type 1 transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is expressed on T-helper/inducer lymphocytes and monocytes. CD3+CD4+ T cells comprise approximately 28% to 58% of normal peripheral blood lymphocytes. CD4 is also expressed on 80% to 95% of normal thymocytes. The CD4 antigen is present in low density on the cell surface of monocytes and in the cytoplasm of monocytes and macrophages (CD3-CD4+). CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV). The SK3 antibody inhibits HIV binding to CD4+ cells.

Specifications

Specifications

CD4
Monoclonal
R718
25 Tests
Primary
Refrigerate Upon Arrival
Flow Cytometry
SK3
Mouse
RUO
Human
Liquid
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