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CD25/IL-2R alpha Antibody (Basiliximab), PerCP - Chimeric, Novus Biologicals™
Human Monoclonal Antibody
Brand: Novus Biologicals NBP2-75902PCP
This item is not returnable.
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Description
CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry.
Specifications
| CD25/IL-2R alpha | |
| Monoclonal | |
| PerCP | |
| PBS with 0.05% Sodium Azide | |
| IL2RA | |
| Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells. | |
| 0.1 mL | |
| Primary | |
| Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation. | |
| Store at 4°C in the dark. |
| Flow Cytometry | |
| Basiliximab | |
| Flow Cytometry | |
| CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR | |
| Human | |
| Protein A purified | |
| Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction | |
| 3559.0 | |
| Human, Cynomolgus Monkey, Rhesus Macaque | |
| IgG1 κ |
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