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Invitrogen™ CCDC134 Monoclonal Antibody (814208)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561868
This item is not returnable.
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Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
Specifications
| CCDC134 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q9H6E4 | |
| CCDC134 | |
| Mouse myeloma cell line NS0-derived recombinant human CCDC134, Thr23-Leu229. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 814208 | |
| Unconjugated | |
| CCDC134 | |
| 2310042L06Rik; AW208859; Ccdc134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 79879 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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