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Invitrogen™ Cardiotrophin 1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5149140
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.
Specifications
| Cardiotrophin 1 | |
| Polyclonal | |
| Unconjugated | |
| CTF1 | |
| cardiophin 1; Cardiotrophin; cardiotrophin 1; Cardiotrophin1; cardiotrophin-1; CT 1; CT1; CT-1; CT-1CT1; CTF 1; Ctf1; IL-6 cytokine family | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 1489 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| Q16619 | |
| CTF1 | |
| E. coli-derived recombinant human Cardiotrophin-1/CT-1, Ser2-Ala201. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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