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ACROBiosystems Canine CD22 Protein, His Tag

Brand:  ACROBiosystems CD2-C52H3-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 17206090

  • 3357.52€ / 1mg
Estimated Shipment: 23-04-2024
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Description

Description

The Cd22 gene is conserved in human, chimpanzee, dog, cow, mouse, and frog. 170 organisms, including rat, have orthologs with human gene Cd22. B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 83.1 kDa.
Specifications

Specifications

83.1 kDa
Canine CD22, His Tag (CD2-C52H3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Arg 718 (Accession # F1PN92-1).
-20°C
CD22
Canine
HEK293
Bio-Markers & CD Antigens
1 mg
Met 1 - Arg 718
CD22, CD22 antigen (Predicted), CD22 molecule
Unconjugated
His Tag
Powder
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