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ACROBiosystems Biotinylated SARS-CoV-2 S protein (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F), His, Avitag
Brand: ACROBiosystems SPN-C82E6-200ug
Additional Details : Weight : 0.00010kg
Description
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 139.8 kDa.Specifications
| QHD43416.1 | |
| 200 μg | |
| Val 16 - Pro 1213 | |
| Spike,S protein,Spike glycoprotein,S glycoprotein,COVID-19 | |
| Precision Avi | |
| His Tag & Avi Tag | |
| Powder |
| 139.8 kDa | |
| Biotinylated SARS-CoV-2 S protein, His,Avitag (SPN-C82E6) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F, R683A, R685A,F817P, A892P, A899P, A942P, K986P, V987P)). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag (at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.) | |
| -20°C | |
| S protein | |
| SARS-CoV-2 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |