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ACROBiosystems Biotinylated Human TROP-2 / TACSTD2 Protein, His, Avitag™
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Product Code. 16408119
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200 μg
25 μg
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200µg
25µg
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16408119 25 μg 25µg
16498109 200 μg 200µg
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Product Code. 16408119 Supplier ACROBiosystems Supplier No. TR2H82E525ug

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Biotinylated Protein

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 31.6 kDa. The protein migrates as 42-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number NP_002344.2
Molecular Weight (g/mol) 31.6 kDa
Quantity 25 μg
Source Biotinylated Human TROP-2, His,Avitag (TR2-H82E5) is expressed from human 293 cells (HEK293). It contains AA His 27 - Thr 274 (Accession # P09758-1).
Immunogen His 27 - Thr 274
Storage Requirements -20°C
Gene Alias TACSTD2,GA733-1,M1S1,TROP2
Common Name TROP-2
Conjugate Precision Avi
Species Human
Protein Tag His Tag and Avi Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype MABSol™ Biotin Labeled Proteins
Purity or Quality Grade >90% as determined by reduced SDS-PAGE
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