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Beta-Tubulin III Mouse, anti-Human, Alexa Fluor 488, Clone: AA10, STEMCELL Technologies

Product Code. 17129011
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100 μg
25 μg
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100µg
25µg
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17129011 25 μg 25µg
17119011 100 μg 100µg
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Product Code. 17129011 Supplier Stemcell Technologies Supplier No. 60100AD.1

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Mouse Monoclonal Antibody

  • The AA10 antibody reacts with beta-tubulin III, an ∼50 - 55 kDa structural protein that is a constituent of tubulin
  • Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha and beta tubulin subunits
  • The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types
  • Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation
  • It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells
  • The AA10 antibody is expected to recognize all mammalian homologs of beta-tubulin III

Specifications

Antigen Beta-Tubulin III
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone AA10
Conjugate Alexa Fluor 488
Host Species Mouse
Quantity 25 μg
Primary or Secondary Primary
Target Species Human, Rat, Mouse
Isotype IgG2a κ
Cell Type Neural Cells, PSC-Derived, Neurons
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