missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Bcl-2 Antibody (BCL2/782) - IHC-Prediluted, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-48277
This item is not returnable.
View return policy
Description
Bcl-2 Monoclonal specifically detects Bcl-2 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications
| Bcl-2 | |
| Monoclonal | |
| Unconjugated | |
| 10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| BCL2 | |
| Recombinant full-length human bcl-2 protein (Uniprot: P10415) | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative. | |
| Store at 4C. | |
| IgG1 κ |
| Immunohistochemistry, Immunohistochemistry (Paraffin) | |
| BCL2/782 | |
| Immunohistochemistry, Immunohistochemistry-Paraffin | |
| apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2 | |
| Mouse | |
| 25.5 kDa | |
| 7 mL | |
| Apoptosis, Autophagy, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors | |
| 596 | |
| Human | |
| Purified |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction