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Invitrogen™ Artemin Monoclonal Antibody (314908)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561182
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| Artemin | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q5T4W7 | |
| ARTN | |
| E. coli-derived recombinant human Artemin, Ala108-Gly220. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Western Blot | |
| 314908 | |
| Unconjugated | |
| ARTN | |
| Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 9048 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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