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tyrosine kinase 2, Mouse, Clone: 5A4, Abnova™
Description
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq
Specifications
Specifications
| Antigen | tyrosine kinase 2 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 5A4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant TYK2. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | TYK2 |
| Gene Accession No. | BC014243 |
| Gene Alias | JTK1 |
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