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GST-π Mouse, Unlabeled, Clone: 3, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 610718
Additional Details : Weight : 0.01000kg
Description
Glutathione-S-Transferases (GSTs) are a family of dimeric proteins that catalyze the S-conjugation of glutathione with many compounds for detoxification. The GSTs are categorized into four classes based on their biochemical and structural properties: α, μ, π, and θ. GST-π is of particular interest because it is over-expressed in many tumors, but is either absent or expressed at low levels in the corresponding normal tissues. This high expression of GST-π is associated with malignant transformation and correlates with a decrease in GST activity. Three different GST-π proteins have been isolated and designated as hGSTP1™A, hGSTP1™B, and hGSTP1™C. These isoforms are nearly identical, varying by only one to two amino acids.
Immunofluorescence, Immunoprecipitation, Western Blotting
Specifications
| GST-π | |
| Monoclonal | |
| 250μg/mL | |
| Glutathione-S-Transferase-π | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at -20°C. |
| Western Blot | |
| 3 | |
| Unconjugated | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Human GST-π aa. 5-210 | |
| 50 μg | |
| Cell Biology | |
| Canine, Human, Mouse, Rat | |
| IgG1 |
For Research Use Only.