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anti-GCK Matched Antibody Pair, Abnova

Product Code. 16142094
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Product Code. 16142094 Supplier Abnova Supplier No. H00002645AP31.1Set

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Description

Includes

Rabbit MaxPab™ affinity purified polyclonal anti-GCK (100μg); Biotinylated rabbit MaxPab™ affinity purified polyclonal anti-GCK (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet β cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

ELISA

Specifications

Antigen GCK
Applications ELISA
Classification Monoclonal/Polyclonal
Conjugate Biotin
Description This antibody pair set comes with matched antibody pair to detect and quantify protein level of human GCK.
Gene GCK
Gene Alias GK/GLK/HHF3/HK4/HKIV/HXKP/MODY2
Gene Symbols GCK
Host Species Rabbit
Purification Method Affinity Purified
Quantity 1 Set
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2645
Includes Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-GCK (100 μg) 2. Detection antibody: biotinylated rabbit MaxPab™ affinity purified polyclonal anti-GCK (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Target Species Human
Content And Storage Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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