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  6. 16164661

fibrillarin, Mouse, Clone: 3E10, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant FBL.

Brand:  Abnova H00002091-M09.100ug


Product Code. 16164661

  • 349.00€ / 100µg

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Description

Description

This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq

Sequence: MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDTTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN
Specifications

Specifications

fibrillarin
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC019260
FBL
FBL (AAH19260.1, 1 a.a. ∼ 321 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Yes
2091
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG2a κ
ELISA
3E10
Mouse monoclonal antibody raised against a full length recombinant FBL.
FBL
FIB/FLRN/RNU3IP1
Mouse
Affinity Purified
RUO
Primary
Human
Antibody
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Safety and Handling

Safety and Handling

Product Identifier
  • FBL monoclonal antibody (M09), clone 3E10

Signal Word
  • Warning

Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2

Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.

Precautionary Statement
  • P102-Keep out of reach of children.
  • P103-Read label before use.
  • P233-Keep container tightly closed.
  • P264-Wash hands thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P404-Store in a closed container.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information
  • MIXTURE LIST-Contains : sodium phosphate dibasic, potassium phosphate monobasic

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