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anti-COMT Matched Antibody Pair, Ab-1, Abnova

Product Code. 16121904
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Product Code. 16121904 Supplier Abnova Supplier No. H00001312AP11.1Set
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Estimated Shipment: 06-10-2026
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Description

Includes

Rabbit MaxPab™ affinity purified polyclonal anti-COMT (100μg); Mouse monoclonal anti-COMT, IgG2bκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

ELISA

Specifications

Antigen COMT
Applications ELISA
Classification Monoclonal/Polyclonal
Conjugate Unconjugated
Description This antibody pair set comes with matched antibody pair to detect and quantify protein level of human COMT.
Gene COMT
Gene Symbols COMT
Host Species Mouse, Rabbit
Purification Method Affinity Purified
Quantity 1 Set
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1312
Includes Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-COMT (100 μg) 2. Detection antibody: mouse monoclonal anti-COMT, IgG2b Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Target Species Human
Content And Storage Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Isotype IgG2b
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