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  6. CDC27 Mouse, Unlabeled, Clone: 35, BD

CDC27 Mouse, Unlabeled, Clone: 35, BD

Product Code. 15865469
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Quantity:
150 μg
50 μg
Unit Size:
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15865469 50 μg 1 set
15875469 150 μg 1 set
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Product Code. 15865469 Supplier BD Biosciences Supplier No. 610454

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Description

Mouse Monoclonal Antibody

CDC16 and CDC27 were discovered in yeast as genes essential for the G2/M transition of the cell cycle. The human homologues of CDC16 and CDC27were cloned and found to encode proteins of 72kDa and 97kDa, respectively. Biochemical and subcellular localization experiments have shown that CDC16 and CDC27 are novel components of the mitotic spindle centrosome in human cells. In HeLa cells, there are about 100,000 copies of each protein per cell. Although its precise role during mitosis remains to be determined, CDC16 appears to be required for cyclin degradation in yeast. Wild type CDC27 is required for the initiation of anaphase. Immunofluorescence studies have shown that both proteins are components of the centrosome in the absence of spindle fibers.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CDC27
Applications Western Blot
Classification Monoclonal
Clone 35
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG2b
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For Research Use Only.

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