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Description
BD IMag™ anti-human CD4 Particles - DM are magnetic nanoparticles that have monoclonal antibody conjugated to their surfaces. These particles are optimized for the positive selection or depletion of CD4-bearing T lymphocytes using the BD IMagnet™. The L200 antibody reacts with CD4 on human, rhesus and cynomolgus macaque, and baboon peripheral blood leukocytes; we have confirmed that the BD IMag™ particles can effectively separate the CD4-bearing cells of rhesus macaque blood. The distribution of CD4 on peripheral leukocytes is similar for both human and monkey. It is on the MHC class II-restricted T helper cells, with the majority of CD4-positive lymphocytes being CD8-negative. It is also found on most thymocytes and at low density on monocytes; it is not found on B or NK cells.
Specifications
| CD4 | |
| Monoclonal | |
| BD IMag-DM | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human HPB-ALL Cell Line | |
| 1 x 109 Cells | |
| Immunology | |
| Baboon, Cynomolgus, Human, Rhesus Monkey | |
| IgG1 κ |
| Flow Cytometry | |
| L200 | |
| L3T4 ; T-cell surface antigen T4/Leu-3; W3/25 ; CD4 antigen (p55) | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
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