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β-Arrestin Mouse, Unlabeled, Clone: 10, BD
Mouse Monoclonal Antibody
343.00€ - 675.00€
Specifications
| Antigen | β-Arrestin |
|---|---|
| Clone | 10 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15805519
|
BD Biosciences
610550 |
50 μg |
343.00€
1 set |
Estimated Shipment: 24-05-2024
Log in to see stock. |
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|
15815519
|
BD Biosciences
610551 |
150 μg |
675.00€
1 set |
Estimated Shipment: 24-05-2024
Log in to see stock. |
|||||
Description
β-Arrestins were discovered due to their ability to modulate interactions between the phosphorylated β2-Adrenergic receptors and G proteins. This modulation results in diminished β2-Adrenergic receptor function, also known as desensitization. Because arrestins are found at the synaptic terminals, they may provide a termination mechanism that allows the neurons to regain their original polarization and respond to a new neurotransmitter stimulus. The C-terminal region of arrestins is involved in selecting the phosphorylated and activated adrenergic receptors. The β-Arrestin1 gene encodes a protein of 418 amino acids with an approximate molecular weight of 55kDa. β-Arrestin1 protein is highly homologous to the 45kDa β-Arrestin2. Both proteins are widely expressed, but are especially abundant in the central nervous system.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifications
| β-Arrestin | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 10 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human, Mouse, Rat | |
| Rat β-Arrestin1 aa. 262-409 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.