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AGR2 Monoclonal Antibody (OTI3F2), TrueMAB™, OriGene

Product Code. 17552284
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17552284 100 μL 100µL
17572284 30 μL 30µL
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Product Code. 17552284 Supplier Origene Technologies Supplier No. TA809754

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Mouse Monoclonal Antibody

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

Specifications

Antigen AGR2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3F2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene AGR2
Gene Accession No. O95994
Gene Alias AG-2, AG2, GOB-4, HAG-2, HEL-S-116, HPC8, PDIA17, XAG-2
Gene Symbols AGR2
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 21-175 of human AGR2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10551
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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