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TMEM66 Polyclonal Antibody, Invitrogen™

Product Code. 15993835
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Quantity:
50 μL
Unit Size:
50µL
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15993835 50 μL 50µL
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Product Code. 15993835 Supplier Invitrogen Supplier No. PA577334

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Description

Rabbit Polyclonal Antibody

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM66
Applications Western Blot
Classification Polyclonal
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.05% sodium azide; pH 7.4
Gene SARAF
Gene Accession No. Q6AYN2, Q8R3Q0, Q96BY9
Gene Alias SOCE-Associated Regulatory Factor
Gene Symbols Saraf
Host Species Rabbit
Immunogen Peptide (C)ELGLSKLKESGKHQS, corresponding to amino acid residues 141-155 of rat SOCE-associated regulatory factor
Purification Method Antigen affinity chromatography
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290796, 51669, 67887
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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