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  7. 3-Isobutyl-1-Methylxanthine, MP Biomedicals™

3-Isobutyl-1-Methylxanthine, MP Biomedicals™

Codice prodotto. 11495222 Sfoglia Tutto MP Biomedical Prodotti
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11405232 1 g 1g
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Codice prodotto. 11495222 Fornitore MP Biomedicals N. del fornitore 02195262.2

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Descrizione

Known as IBMX. 3-Isobutyl-1-Methylxanthine, MP Biomedicals is a potent, non-specific inhibitor of cAMP and cGMP phosphodiesterases, significantly more effective than theophylline. This inhibition activates PKA, leading to decreased proliferation, increase

A non-specific inhibitor of adenosine 3',5'-cyclic monophosphate phosphodiesterase (cAMP PDE)4, significantly more effective than theophylline. Also inhibits cGMP phosphodiesterases. IBMX inhibits cyclic nucleotide PDE with subsequent inhibition of cyclic nucleotide hydrolysis, resulting in accumulation of cyclic AMP and guanosine 3',5'-cyclic monophosphate.

  • Inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3μM)
  • Serves as an adenosine receptor antagonist
  • Inhibits ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells
  • Induces calcium release from intracellular stores in sensory neurons
  • Inhibits the growth of carcinoma cells both in vivo and in vitro in mice
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 28822-58-4
Molecular Formula C10H14N4O2
Molecular Weight (g/mol) 222.25
MDL Number MFCD00005584
InChI Key APIXJSLKIYYUKG-UHFFFAOYSA-N
Synonym 3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine
PubChem CID 3758
ChEBI CHEBI:43253
IUPAC Name 1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
SMILES CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O

Specifica

Melting Point 195°C to 202°C
Quantity 250 mg
Formula Weight 222.25
Physical Form Powder

Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • 3-Isobutyl-1-methylxanthine
 Avvertenza
  • Warning
 Categoria di pericolo
  • Acute toxicity Category 4
 Indicazioni di pericolo
  • H302-Harmful if swallowed.
 Consigli di prudenza
  • P264-Wash thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P330-Rinse mouth.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Informazioni supplementari
  • MIXTURE LIST-Contain: 3-Isobutyl-1-methylxanthine
Titolo del prodotto
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