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  7. 1,2,2,6,6-Pentamethylpiperidine, 97%

1,2,2,6,6-Pentamethylpiperidine, 97%

Product Code. 11392859
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1 g
5 g
Unit Size:
1g
5g
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Product Code. 11392859

Brand: Thermo Scientific Alfa Aesar H27729.03

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Description

CAS: 79-55-0 | C10H21N | 155.285 g/mol

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.

Solubility
Soluble in toluene, dimethylformamide.

Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 79-55-0
Molecular Formula C10H21N
Molecular Weight (g/mol) 155.285
MDL Number MFCD00006493
InChI Key XULIXFLCVXWHRF-UHFFFAOYSA-N
Synonym pempidine, pyrilene, perolysen, tenormal, piperidine, 1,2,2,6,6-pentamethyl, pempidina dcit, pempidine inn:ban, pempidinum inn-latin, unii-n5i18ji9d6, 1,2,2,6,6-pentamethyl-piperidine
PubChem CID 6603
IUPAC Name 1,2,2,6,6-pentamethylpiperidine
SMILES CC1(CCCC(N1C)(C)C)C

Specifications

Density 0.858
Boiling Point 187°C to 188°C
Flash Point 50°C (122°F)
Odor Amine-like
Quantity 1 g
UN Number UN1992
Beilstein 103806
Sensitivity Air Sensitive
Merck Index 14,7080
Solubility Information Soluble in toluene,dimethylformamide.
Formula Weight 155.28
Percent Purity 97%
Chemical Name or Material 1,2,2,6,6-Pentamethylpiperidine
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Safety and Handling

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Product Identifier
  • 1,2,2,6,6-Pentamethylpiperidine
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
  • Serious eye damage/eye irritation Category 2
  • Flammable liquid Category 3
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H226-Flammable liquid and vapour.
  • H301-Toxic if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
 Supplemental information
  • MIXTURE LIST-Contains : 1,2,2,6,6-Pentamethylpiperidine
SDS

RUO – Research Use Only

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