The Maybridge portfolio offers a comprehensive range of chemistry products and services tailored to the drug discovery and biotechnology sector. For over 50 years, Maybridge has been at the forefront of innovative heterocyclic building block and screening compound design, fuelled by the desire to access novel molecules of pharmaceutical interest.
The Maybridge portfolio is driven by a keen understanding of the needs of the medicinal chemist and is designed to expedite the drug discovery process.
The ultimate diversity screening library. Our new offering takes away the need to choose between different libraries by providing the ultimate coverage of drug-like chemical space with a single library. Building on over 50 years of expertise in designing industry leading screening libraries the pre-plated HitCreator represents the diversity of a 500,000 compound library distilled to 14,000 molecules. Each Maybridge HitCreator is conveniently supplied as dry films in Thermo Scientific Matrix 96 shallow-well plates or 384-well microplates.
Hit-to-Lead Building Blocks
The core of the Maybridge building block collection, these pharmacophorically rich intermediates are specifically designed for medicinal chemistry, allowing logical SAR development and Hit-to-Lead optimization.
Many will be of particular interest as “privileged structures” while others bearing solubilizing moieties add to the pharmacokinetic profile of drug molecules.
A highly diverse set of over 53,000 hit-like and lead-like molecules widely acknowledged as a critical tool in screening campaigns.
30,000 small compounds (mw<300) taken from the complete Maybridge collection for use in fragment screening to further accelerate the identification of lead compounds.
Ro3 2500 Diversity Fragment Library
The Maybridge Ro3 Diversity Library is a diverse selection of 2500 products from the complete Fragment Collection. It is fully Ro3 compliant with assured quality of >= 95% purity and assured solubility.
14,400 compounds selected to represent the overall diversity of the screening collection available pre-plated at 1µmol in 96-well plates or .25µmol in 384-well plates.
The entire Maybridge screening collection of over 53,000 compounds is available off-the-shelf, pre-plated as 1umol dry films in 96 well plate format. Exceptional diversity and outstanding value!
Maybridge Chiral Resolution Screening and Purification Kits – Using these ready-to-use kits can reduce time to identify the best separation conditions to just one day.