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Tocris Bioscience™ YM 58483

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
YM 58483 is a blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes). Inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin -induced sustained Ca2+ influx (IC50 = 100 nM). Displays immuno-modulatory and anti-inflammatory effects; suppresses cytokine production and proliferation of T cells in vitro.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 421.32 |
| Purity | >99% |
| Molecular Weight (g/mol) | 421.321 |
| Chemical Name or Material | YM 58483 |
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