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Tocris Bioscience™ TM 5441
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Product Code. 30002156
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30002156

Brand: Tocris Bioscience™ 6194/10

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This item is not returnable. View return policy

Description

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 3.58 - 60.3 μM). Increases apoptosis in human cancer cell lines. Reduces senescence and increases lifespan in mouse models of ageing (kl/kl). Inhibits L-NAME (Cat.No. 0665) induced systolic blood pressure increases, telomere length reduction and cardiac hypertrophy in mice. Renoprotective. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Solubility Soluble to 100mM in DMSO
Formula Weight 450.8
Physical Form Solid
Purity >98%
Chemical Name or Material 5-Chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt
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